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Questions and Answers
What effects does Ibuprofen have on weightlifting and exercising? Just wondering: if I take, for example, 600 mg of ibuprofen half an hour before a workout, would it do anything like inhibit or promote muscle growth?

Nick B replied: "well, im not totally sure, but i take 3 ibuprofens right before i lift weights, so my muscles are pain free when im lifting heavy weights."

T.J. replied: "It would have no effect on muscle growth."

Josh C replied: "I don't think they'd help or hurt muscle growth. Ibuprofen is an anti-inflammatory, so it helps with muscle pain while you work out, but I don't think it has any large affect either way other than that."

Ibuprofen.? Why do people become addicted to Ibuprofen? Besides that fact that it can ease pain, why do some people take it on a regular basis or as a non-medical drug. For example, I'm in high school and a schoomate of mine (A frequent weed smoker) asked me if I had some Ibuprofen. That wasn't the only time I was asked for some. But I'm just wondering if it creates some sort of high or anything.

Ttrriissttiin replied: "Don't think it has a "high" associated with it, maybe because they always have headaches from the drug withdrawals."

NMFlamingo replied: "Nope.... ibuprofen is not addictive. I think some people just can't tolerate any pain at all. TV is constantly showing us that no matter what the problem is, there's a pill for it. If more of us just lived healthy lives and ate healthy foods (mostly), we wouldn't need pain pills, or most of the other pills."

ava replied: "I never heard of asprin being adictive, codien or vicodin maybe. Asprin ruins the lining of the stomach so only use in moderation to treat pain and swelling."

Icy gazpacho replied: "I use Ibuprofen all the time to reduce muscle inflammation (shoulder injury).... but I don't think it is addictive."

Ashley replied: "i take ibuprofen very often, because i get many headaches or cramps or other various pains. it's not addictive, and there's definitely no high assiciated i just think people rely on it to cure their pains too much (that includes me lol) if your friend smokes weed, they're probably having withdrawals while their in school, and that can include many different pains that ibuprofen can help with. i think it can cause damage if you use it frequently enough over a long period of time tho. so maybe your friend should ease off the weed and the ibuprofen to avoid future health problems"

phillip w replied: "It's when they are coming down the pain starts."

sweet_susy59 replied: "Nobody should get addicted to Ibuprofen. You can't get a high on this stuff, because it's only a painkiller. I'm allergic to aspirin so I can't take ibuprofen. I take Tylenol arthritis, 650 mg. per tablet, and extra strength Tylenol comes in 500 mg. per tablet, or capsule. Lots of people have to take Ibuprofen on a regular basis, because they live with pain on a regular basis. I live with lots of pain every single day, and I'm allergic to aspirin, and lots of other pills. I can only take Tylenol arthritis, or regular Tylenol. It definitely don't make you get high."

Pain relievers other than tylenol and ibuprofen? For small to moderate pain (such as back and neck aches, as well as head aches), what do you think is the best type of Over-The-Counter medicine to take? I currently take ibuprofen. I also know about tylenol, but I have a concern that there may be something that is better for you than these medicines. Like natural supplements, for example? What do you think works the best and is the best for your health?

Air Ick replied: "Advil and Motrin"

"Concerned" replied: "Ibuprofen is GENERIC for Motrin & Advil (just look at the active ingredient on the back of the package. Ibuprofen works pretty well and is available as a 200mg Over-the-counter. if 1 tablet is not sufficient, you can certainly take 2. In fact, some people may take 4 at once (800mg). But for you, start with a step wise approach when taking more tablets, so dont just start taking 800mg without trying 400, or 600mg. My recommendation for neck aches would be one of the two you mentioned. Tylenol, being my very first recommendation. Take 2 325mg tablets or one extra strenght (500mg) tablet. Goodluck"

Rock N Roll Saved My Soul replied: "I have been taking Excedrin Back & Body.. from the website: "Excedrin Back & Body has a dual-ingredient formula that works two ways—as a pain reliever and a pain blocker right where it hurts." "

Brian H replied: "You have to be careful with natural supplements as there is typically no research done on them. Those that have been proven effective are generally taken up by companies and engineered into modern drugs (this is the origin of aspirin). I've never heard a pharmacist recommend anything "natural" for pain. Advil and Motrin are both identically ibuprofen. Excedrin is an option; essentially Extra Strength Tylenol and caffeine. Another anti-inflammatory (NSAID) commonly used for pain relief is naproxen (Aleve). There honestly isn't too much else over the counter. Most OTCs are generally made using the same active ingredients, and this is what you'll always want to check on the box. Grace and peace!"

Ummon replied: "Naproxen is a relative of Ibuprofen - both are primarily anti-inflammatories, they are related so you could try naproxen. Aspirin is also somewhat similar in action to Naproxen and Ibuprofen, and it has some good analgesic effect as well, so it is a good bet. Tylenol is not an anti-inflammatory so it will be less effective for your neck. I wouldn't use it for this. If you go to things like codiene (available in Canada OTC), you may get pain relief, but poor anti-inflammation so the pain returns as soon as it wears off. Motrin and Advil are just Ibuprofen under another name, so you are already using those. Excedrin back and body is aspirin mixed with tylenol. Try the aspirin first, as I said, because tylenol is not going to buy you much. I think you best bet is taking 2 aspirin with a lot of water next time you have neck pain and see how it responds. You can take more, and aspirin is also a blood thinner so it is decent for preventing strokes and heart attacks. Aspirin is very potent at these kinds of injuries, and was originally "natural" (comes from a tree). In terms of alternative therapies, nothing is going to work like the anti-inflammatories, opiates and then narcotics for neck pain, but ideally you want to stick with the first group."

Rebecca S replied: "Ibuprofen and Naproxen(Advil or Aleve) work best for pain from an injury because they help with swelling. The down side to these drugs is that they can cause stomach ulcers or bleeding. Tylenol is a general pain reliever that can reduce a fever. It is also less likely to cause stomach issues and react with any prescription medication. Natural Supplements are not regulated by the FDA and should be avoided at all cost. It all depends on the cause of your pain and your current health. If your pain is not helped by these pain relievers call your doctor as you may be able to double the recommended dose."

pixysnot replied: "for back and neck aches, and any kind of muscle ache, nothing beats a bean-bag style microwaveable heating pad. They sell really expensive ones in the mall that are full of fragrant herbs and stuff, but you can make one yourself really cheap. My grandma had a homemade one she would let us use when we stayed there, it was filled with corn. I must say if you are making one yourself, try using old t-shirt material cuz it's comfy! Microwave 1 minute to start with and then if it needs more go 30 seconds at a time. Otherwise Aleve works okay on muscle aches too. I am a caffeine addict, so Excedrin works well on me for headaches, but supposedly there's herbs and stuff you can add to the DIY heating pad to help headaches too."

Isis Is: R.I.P. JUNO replied: "i can't take Tylenol anymore. and ALEVE works better for me than ibuprofen."

Searching For Answers replied: "Pain stop is wonderful"

What is the general difference between a name brand non-precription drug and a generic brand? For example: IBUPROFEN > Advil (Name brand) > Equate (Generic brand) How are they different? Chemistry wise?

SC replied: "Biggest difference: Who makes it There may be differences in the inactive ingredients which may mean different taste or texture."

Nas replied: "Hi, both drugs are equal, but the brand drug costs more because you have to pay for the brand too."

sonnydays15 replied: "Usually, the drug itself is the same. What is different are usually the adjuvants or additional things that are put into the drug to make it work. These might result in slightly more side-effects, or bitter taste, etc. But nothing serious. According to the FDA, a drug needs to show bioequivalence. A generic drug needs to show the same biological effect with about the same toxicity that a name brand drug would. So unless you're buying your drugs from Mexico, or you're worried or don't like a particular side-effect, there's no real difference."

a simple man replied: "Chemistry-wise, the difference is in the standards applied, Generic drug are chemically the same but the dosage equivalence allowed by low is 80 to 120 percent of the prescription labeled dose. Meaning, if you are on thyroid medication, the generic can have 80 mcg or 120 mcg and still be labeled as 100 mcg. This way you can get 120 mcg one month and 80 mcg the next month and wonder why it is not working. Old Doc"

toxdoc333 replied: "Generic (sometimes called off label) meds contain the same primary active ingredient as the brand name. In some cases, although the drugs may have bioequivalency (meaning the do the same thing) they may be different in other ways. For example, some generic meds have different pharmacokinetics because of the way the generic is formulated or compounded. Differences in additives, buffering or other manufacturing techniques may result in less of the drug getting into your blood or time to reach maximum concentration may be longer. The drugs generally will have the same overall effect and frankly, the differences just noted may not be noticeable to the patient, but they are there."

Can you take, for example, ibuprofen before waxing hair for pain reduction?? Have you ever done this? I have Polycystic Ovaries and as a result am a hair monster all over!!! Even on my face which I hate!! I heard that some people before waxing, plucking etc. take a painkiller beforehand to reduce pain!! I hope this works!! Which type of painkiller would I need e.g. paracetamol, codeine, ibuprofen etc.. How long would I need to leave in between taking the tablets and the plucking, how long does the pain reduction last etc.. I don't care about pain AFTER plucking coz the hairs out then isn't it!! I just hate the pain when I AM plucking!!! Thanks and love xxxxxx

marys.momma replied: "Most over-the-counter pain medicines — aspirin, ibuprofen, or acetaminophen — take about fifteen to twenty minutes to kick in, and last about three to four hours. However, I don't know anything about paracetamol or codeine. I have noticed that when I've taken aspirin for a headache or sore muscles, the pain sometimes increases for about five minutes at the fifteen-minute mark, and then fades. I don't know why this occurs, but I have learned to resist the temptation to take more than the standard dose at that time. So in your case, I'd say to wait twenty or thirty minutes after taking the medicine, before starting to pluck. Be sure to pluck each hair straight out from the same direction the hair is growing. More permanent methods of hair removal are available, such as electrolysis or laser treatments. Look them up on the Internet with Google.com -- there's lots of information there. They may or may not be appropriate for you. Perhaps a visit to an endocrinologist would be a good idea. There might be hormone treatments that could help your condition."

DenimNleatherRocker replied: "I have PCOS but have never used pain relief before waxing. Maybe try going to a health and beauty shop to get it done..the whole atmosphere is that relaxed and they have special balms to put on afterwards to prevent any unnecessary pain. They could also talk through electrolasis treatment which is little electric impulses that reduces hair growth. Good luck!"

Ann M replied: "ibuprofen is a muscle relaxant and works on headaches but nothing other than that and muscle based things - find a different painkiller but it seems like a good idea =] xxx"

What are examples of organic molecules? I have a chemistry project. It isn't too bad, I have to pick a specific organic molecule and make a 3D model of its structure, and prepare a report. I was earlier trying to do ibuprofen but couldn't find research on the series of reactions that make it. Please give me some easy organic molecules which good structures, not too simple, not too hard. but please make sure when i google, i will be able to find information on the reactions that produce it.

Chad replied: "do ibuprofen! if you google "Ibuprofen synthesis" you can find some descriptions on how it is made. The rsc link looks pretty good."

Ibuprofen, Aspirin and Paracetemol: Which is best for which type of pain? For example which out of those 3 is best for these common pains: Toothache Period pain Backache Headache Muscle pains etc Just wondering if there's much difference between them and if one would be better than another for different types of pain.

sarasara replied: "ibuprofen is the best painkiller, but you can take paracetamol in between too if the pain is that bad...stay away from aspirin if you're/have been drinking"

stressedclaire replied: "because ibuprofen is also an anti-inflammatory then it is good for muscular pain, also backache etc. anything where there is inflammation"

Incontrol replied: "I find Paracetamol good for toothache, headache for the rest Ibuprofen. Aspirin I would never touch.But really it what suites you."

paulterrie replied: "All are different but the same if you know what I mean all are pain killers but ibuprofen is an anti inflammatory ( backache muscle pain ) and must be taken with food as can give you terrible indigestion aspirin is a good pain killer ( toothache headache )but can cause problems with the stomach Paracetamol is a good all rounder as a pain killer and has little or no side effects and can be used for children ."

Emma replied: "I would take ibuprofen (400mg- if you are old enough) as it takes down the inflammation... then paracetamol.... and if you are really in pain or have an infection you can take paracetamol (1000mg) and ibuprofen (400mg) together as the drug bases are different Aspirin can be the most harsh drug on your liver... so I would take this last out of the three.. Never take aspirin with ibuprofen But all are good for pain relief if taken as recommended.."

ADZE replied: "Aspirin is a big no no,wife took the for a few months on prescription,finished up in A & E having to have two ltr`s of blood.Ibuprofen is OK so is Paracetamol is OK, but you have to be carefull with both becouse of over dosing.Leave any pain reliever alone that contain asprin."

Bren replied: "for all those listed except headache ibuprofen and aspirin are the best as they are anti inflammatory, it may well work for headache too but paracetamol may be better, u can take ibuprofen or aspirin and paracetamol but never ibuprofen and aspirin together as they are similar medicines. asthmatics and people with stomach/bleeding problems have to beware of ibuprofen and aspirin"

fadzlul replied: "i just know about the aspirin & paracetamol...both have analgesic & anti pyretic effect. but the diffrent is, the paracetamol doesn't have anti inflammation effect, because it acts at the brain. aspirin act at the site of pain. so, if u have pain, and it is not related to injury, u can use paracetamol. but for your information, paracetamol have anti platlet effect. it can lead to prolong the bleeding time.."

bookworm replied: "If you hav'nt got ibruprofen, then use paracetemol.....however please remember that an overdose of paracetemol can lead to irrepairable liver damage. That is NOT to say you can't overdose on Ibruprofen, it's just that I don't know what the effect on the body is for someone taking too much of it. Something I find really usefull with ibruprofen is that it is a really good hangover cure...taken before I go to bed after a heavy session, I wake up every time hangover free !! What's that worth!! People get hangovers because the alchohol they drink shrinks the covering around the brain......it 'INFLAMES' it, and Ibruprofen is ...wait for it........an anti-inflammatory ! ! MAGIC!! Stay away from Aspirin if you can....it used to be the stock remedy for all aches and pains but pills and potions are now regulated much more strictly since aspirin was discovered and it is nearly ........obsolete ?? Is that the word I'm looking for? Yeah ! Happy celebrating over Christmas and keep some Ibruprofen ready for the day after. Now for the disclaimer bit....This works for me!....I do not suggest that it works for anyone else nor do I recommend anyone else to try it! Please read all the instructions on the outside of all medicines and pills.If you are not sure, ask your doctor before taking anything orally for pain relief. There, that's done!..'bye for now."

Ghanshyam S replied: "Asprin should b excluded 4m ur list f drugs... it causes plenty f gastric erosions.... it may cause acute gastritis... Paracetamol is d safest f all.... bt its 4 mild pain n a poor antiinflammatory drug... so i think ibuprofen should b d best in these three...."

T C replied: "I swear by Ibuprofen for all aches & pains."

Kanst replied: "Ibuprofen, Paracetamol is good for a fever though. Aspirin I leave alone unless it's all I have got! If the pain is really bad and one type doesn't help, you can take paracetamol at the same time as ibuprofen - whack the pain from two fronts (just don't mix ibuprofen/aspirin/or other NSAIDS at the same time). And don't overdose on paracetamol - it'll kill your liver - slowly!"

Kerry K replied: "Ibuprofen is really good for muscle pain, but you have to take it regularly 3 times a day to get the full benefit usually takes a couple of days to start working properly. Aspirin and paracetamol are really good for headaches, toothache, period pain etc."

out of curiosity how many boots own brand ibuprofen long lasting tablets would it take? to kill you if im 13 and i weigh 58kg and i had lunch at 1 today so i do have food in my stomach and wat would happen if i took 5 or 6 or 7 or 8 i mean like 5 would make me sick 6 would make me pass out and 9 would kill me for example like wat happens????? because i just took 10 and now im really worried

RichyB replied: "you disgust me"

Neil B replied: "My doctor told me it would be OK to take as many as six at a time to help with my back pain. But only for a few days at a time."

Can anyone please suggest a pharmaceutical process that has been made "green"? An example I have is of Ibuprofen being synthesised in a 3-step process instead of 6 steps meaning less waste produced but can't think of any others. Just looking for examples of any drug which is produced using a more efficient catalyst in place of a toxic solvent or something along those lines. Thanks in advance :)

loxi replied: "I can think of lots of green processes for various organic compounds, but the only "drug" i can think of is Vitamin C. (not sure if this is the type of thing you looking for) orginal synthetic route: step A D-glucose to D sorbitol using H2 /cat step B D-sorbitol to L- sorbose using aceterbacter xylinium step C L-sorbose to 2- keto-L-Gluconic acid using ch3coch3/h2so4 then kmno4 then H+ step D 2- keto-L-Gluconic acid to asorbic acid (aka vit C) green improvements to route: step B uses acetobacter suboxydans this is a Ni resistant bacteria as previous bacteria died due to stainless steal, less waste? step C ch3coch3/h2so4 then kMno4 then H+ is replaced with Pd -C and air. (Mn waste is bad) step D uses a enzymatic route instead. (no toxic meOH) Although now i think there is a a single fermentation step from galactose, which is patented so I don't have details."

Siz_1 replied: "Steve Ley's group at Cambridge University have just published a continous flow synthesis of Viagra. The link below is a explination of Steve's work and ethos. Bascially using flow chemisty and not isolating intermediates you save energy in heating / cooling / drying. You will probably use less solvents. There are examples at Pfizer and GSK of scaled continous reactions, although they are not in the public domain."

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